Inflammasome Publications

IC 100 Publications

IC 100 Mechanism of Action

IC 100 improves functional outcomes in animal model of multiple sclerosis

Role of inflammasomes in multiple sclerosis

Role of inflammasomes in aging (inflammaging)

Inflammasome signaling proteins in early and intermediate states of Alzheimer’s disease

Inflammasome activation in traumatic brain injury and Alzheimer’s disease

Genetic predisposition to Alzheimer's disease alters inflammasome activity after traumatic brain injury

Traumatic Brain Injury-Induced Acute Lung Injury: Activation and Inhibition of a Neural-Respiratory-Inflammasome Axis

Molecular Platform in Neurons Regulates Inflammation after Spinal Cord Injury

Role of microglial inflammasome activation in pyroptotic cell death following penetrating traumatic brain injury

Neutralization of NLRP1 inflammasome reduces innate immune response and improves histopathology after traumatic brain injury

Inflammasome ASC Inhibitor IC 100 As Treatment for Retinopathy of Prematurity

About Inflammasomes

Biotechs explore the next generation of inflammasome targets, with caution

Inflammasomes: mechanism of action, role in disease, and therapeutics.

The intra- and extracellular functions of ASC specks.

The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.

Inflammasomes and autoimmunity.

Inflammasomes and CNS Conditions

Exosome-mediated inflammasome signaling after central nervous system injury.

Activation and regulation of cellular inflammasomes: gaps in our knowledge for central nervous system injury.

Inflammasome Proteins as Biomarkers

Inflammasome Proteins As Biomarkers of Multiple Sclerosis.

Inflammasome proteins as biomarkers of traumatic brain injury.

Defective Inflammatory Pathways in Never-Treated Depressed Patients Are Associated with Poor Treatment Response.